Element card for assessment element A0024 in HTA Core Model Application for Medical and Surgical Interventions (2.0) application

A. Health Problem and Current Use of the Technology

Current Management of the Condition

How is the disease or health condition currently diagnosed according to published guidelines and in practice?

Core

The effectiveness of an intervention may vary in differently diagnosed populations. A sensitive test tends to have low specificity such that there are several people who do not have the condition among the test-positive population. The effectiveness of an intervention in that population may be lower than in a population examined with a less sensitive test (but with more true positive cases). It is important to point out possible discrepancies between guidelines and actual practice.

Sources: Clinical guidelines and published utilisation reviews; in the absence of these, clinical experts survey. See Appendix 1. Method: Systematic review of clinical guidelines. Quality appraisal of guidelines can be done using e.g. AGREE II Instrument. For practice mapping, a pragmatic review or listing of available information is sufficient. Flowcharts are illustrative in reporting diagnostic pathways.

Critical
Partial

Burls 2000 {1}, Velasco 2002 {25}, Liberati 1997 {3}, Imaz-Iglesia 1999, Kristensen 2007 {24}