Result card

  • EFF9: What is the effect of Abdominal Aorta Aneurysm Screening on generic health-related quality of life?
English

What is the effect of Abdominal Aorta Aneurysm Screening on generic health-related quality of life?

Authors: Katrine Frønsdal, Stefan Sauerland and Ingvil Sæterdal

Internal reviewers: Pseudo164 Pseudo164, Pseudo179 Pseudo179, Pseudo71 Pseudo71, Pseudo98 Pseudo98

Evidence issued from the basic literature search (done for the whole project) was used to assess this element. Methods for reporting clinical effectiveness data and assessment of strength of evidence are as described in Domain Methodology.

One SR was included to assess the effect of AAA screening on QoL in terms of state anxiety, depression and mental QoL (Collins 2011). This SR was determined to be of high quality (Appendix EFF-2, section 2). GRADE Summaries of findings (SoF) tables for these outcomes are shown in Appendix EFF-2 Section 5. No information on gender or age distribution was provided. Outcomes assessed were anxiety, depression and mental QoL. Anxiety was measured using STAI, the state scale of the state-trait anxiety inventory (Spielberger 1970), depression was measured using HADS, the state Hospital Anxiety and Depression Scale (Zigmond & Snait 1983), whereas mental QoL was measured using Short Form Health Survey SF-36 (Ware & Sherbourne 1992).

As this research question also is covered in the Social Aspects domain, result cards SOC1, SOC2, SOC3 and SOC4 are referred to for EFF9.

Anxiety

In the SR by Collins et al., in the one RCT that assessed anxiety, a total of 1,956 participants were randomised to an invitation to attend screening for AAA (n=1,230) or no invitation (control; n=726). Anxiety was significantly reduced in the screened group: the standard mean difference (Std.MD) was -0.12 with a 95% CI of -0.21 to -0.02 ((see SoF table in Appendix EFF-2 Section 5) P not indicated).

Depression

In the Collins et al. SR, depression was assessed in the same RCT, which included a total of 1,956 participants randomised to an invitation to attend screening for AAA (n=1,230) or no invitation (control; n=726). Depression was significantly reduced in the screened group:  the Std.MD was -0.11 with 95% CI from -0.20 to -0.02 (P was not indicated; see SoF table in Appendix EFF-2 Section 5).

Mental Quality of Life (QoL)

Mental QoL was also assessed in the RCT included in the Collins et al. SR in which a total of 1,956 participants were randomised to an invitation to attend screening for AAA (n=1,230) or no invitation (control; n=726). Mental QoL score was better in the screened group but not significantly so: Std.MD was 0.07 with 95% CI from -0.02 to 0.16 (P was not indicated; see SoF table in Appendix EFF-2 Section 5).

Critical
Completely
Frønsdal K, Sæterdal S Result Card EFF9 In: Frønsdal K, Sæterdal S Clinical Effectiveness In: Jefferson T, Vicari N, Frønsdal K [eds.]. Abdominal Aorta Aneurysm Screening [Core HTA], Agenzia nationale per i servizi sanitari regionali (age.na.s), Italy; 2013. [cited 30 June 2022]. Available from: http://corehta.info/ViewCover.aspx?id=106