Result card

  • EFF19: How does Abdominal Aorta Aneurysm Screening modify the need for other technologies and use of resources?
English

How does Abdominal Aorta Aneurysm Screening modify the need for other technologies and use of resources?

Authors: Katrine Frønsdal, Stefan Sauerland and Ingvil Sæterdal

Internal reviewers: Pseudo164 Pseudo164, Pseudo179 Pseudo179, Pseudo71 Pseudo71, Pseudo98 Pseudo98

Evidence issued from the basic literature search (done for the whole project) is used to assess this element. Methods for reporting clinical effectiveness data and assessment of strength of evidence are as described in Domain Methodology.

One SR was included to assess the effect of AAA screening on planned and emergency operations (Lindholt & Norman 2008). The SR was determined to be of medium quality (Appendix EFF-2, Section 2). GRADE SoF tables for these outcomes are shown in Appendix EFF-2 Section 5.

As this research question also is covered in the Organisational Aspects domain (ORG), result card ORG19 is therefore referred to for EFF19.

Planned operations in men (long-term)

The SR by Lindholt & Norman was the most recent SR assessing long-term (i.e. after 7 to 15 years) planned operations in men (Lindholt & Norman 2008). Three RCTs included in total 86,479 men aged between 64 and 83 years randomised to an invitation to attend screening for AAA (n=43,167) or no invitation (control; n=43,312). Pooled analysis of the three ORs showed a significant increase in planned operations (long-term) in the screened group (see SoF table in Appendix EFF-2 Section 5). The fixed-effect OR was 2.81 with 95% CI from 2.40 to 3.30, P<0.00001.

Planned operations in men (medium term)

The SR by Lindholt & Norman was the most recent SR assessing medium term (i.e. after 3½ to 5 years) planned operations in men (Lindholt & Norman 2008). Four RCTs included a total of 125,576 men aged between 64 and 83 years randomised to an invitation to attend screening for AAA (n=62,729) or no invitation (control; n=62,847). Pooled analysis of the four ORs showed a significant increase in planned operations (medium term) in the screened group (see SoF table in Appendix EFF-2 Section 5). The random-effect OR was 3.27 with 95% CI from 2.14 to 5.00, P<0.00001.

Emergency operations in men (long-term)

The SR by Lindholt & Norman was the most recent SR assessing long-term (i.e. after 7 to 15 years) emergency operations in men (Lindholt & Norman 2008). Three RCTs included a total of 86,479 men aged between 64 and 83 years randomised to an invitation to attend screening for AAA (n=43,167) or no invitation (control; n=43,312). Pooled analysis of the three ORs showed a significant reduction in emergency operations in the screened group (see SoF table in Appendix EFF-2 Section 5). The random-effect OR was 0.48 with 95% CI from 0.28 to 0.83, P=0.009.

Emergency operations in men (medium term)

The SR by Lindholt & Norman was the most recent SR assessing medium term (i.e. after 3½ to 5 years) emergency operations in men (Lindholt & Norman 2008). Four RCTs included a total of 125,576 men aged between 64 and 83 years randomised to an invitation to attend screening for AAA (n=62,729) or no invitation (control; n=62,847). Pooled analysis of the four ORs showed a significant reduction in emergency operations in the screened group (see SoF table in Appendix EFF-2 Section 5). The fixed-effect OR was 0.55 with 95% CI from 0.39 to 0.76, P=0.0003.

Critical
Completely
Frønsdal K, Sæterdal S Result Card EFF19 In: Frønsdal K, Sæterdal S Clinical Effectiveness In: Jefferson T, Vicari N, Frønsdal K [eds.]. Abdominal Aorta Aneurysm Screening [Core HTA], Agenzia nationale per i servizi sanitari regionali (age.na.s), Italy; 2013. [cited 30 June 2022]. Available from: http://corehta.info/ViewCover.aspx?id=106